• br Discussion Treatment of patients with vaginal leiomyosarc

  2019-06-27

  

  Discussion Treatment of patients with vaginal leiomyosarcoma is challenging because of the rarity of this disease and a lack of controlled clinical trials comparing management strategies. At this time primary surgery remains the mainstay of management of vaginal leiomyosarcoma. Treatment plans sh

• br How do you manage patients on

  2019-06-27

  

  How do you manage patients on intravenous bone-targeted agents who require dental work? For patients who are on IV bisphosphonate therapy and require dento-alveolar procedures there is a suggestion that prophylactic antibiotic use around the procedure may be helpful in reducing ONJ risk [45,49].

• br Conflict of interest br Introduction Bladder cancer

  2019-06-27

  

  Conflict of interest Introduction Bladder cancer is one of the most common cancers in the world. It is estimated that around 74,000 new cases of cytokine inhibitors cancer and 16,000 bladder cancer-related deaths will occur in the United States in 2015. It is prominent in men and in the elder

• It is noteworthy that even with low

  2019-06-27

  

  It is noteworthy that, even with low tumor burden in these patients following CR, peak value at CR status is still a useful indicator for OS, both in the whole cohort, and more importantly, in the intermediate-risk subgroup. Slope is mainly determined by tissue vascularization and perfusion, but cap

• br Material and methods The study population was selected

  2019-06-27

  

  Material and methods The study population was selected from the National Cancer Institute’s SEER database. The SEER database collects data from 18 geographic registries, covering approximately 28% of the U.S. population [17]. The SEER⁎Stat software (Version 8.0.4; NCI; Bethesda, MD) was used to i

• br Discovery of S PR as a CBA sensor

  2019-06-27

  

  Discovery of S1PR2 as a CBA sensor in the liver Early studies reported that activation of the ERK1/2 and AKT signaling pathways by CBAs was PTX-sensitive, suggesting a role for a Gαi-linked GPCR. To identify which GPCR activates the ERK1/2 and AKT signaling pathways, the cDNAs encoding more than

• En cuanto a la Accountability

  2019-06-27

  

  En cuanto a la Accountability horizontal, Przeworski planteó que O’Donnell utilizaba el concepto para referirse a que en América Latina las relaciones interinstitucionales, los pesos y contrapesos entre poderes e instancias del Estado eran débiles, por lo cual se terminaban delegando las decisiones

• br En general los resultados electorales de

  2019-06-27

  

  En general, los resultados electorales de 2011 demuestran la identificación y cercanía lograda entre los movimientos sociales y Ollanta Humala, por lo menos en términos de adhesión electoral, la misma que se mantuvo en el tiempo pues en 2006 también estos sectores le otorgaron su voto. Así, la ele

• The diagnosis of PTC based on

  2019-06-27

  

  The diagnosis of PTC, based on the Modified Dandy Criteria, is made when a patient exhibits an elevated LP opening pressure above 25cm H20 with normal CSF composition and radiologic findings, and no other explanation for the rise in intracranial pressure [6]. The most common presenting symptom occur

• br In the current issue of Soha

  2019-06-27

  

  In the current issue of , Soha Sobhy and colleagues have compiled the first systematic review and meta-analysis of anaesthesia-related maternal mortality in low-income and middle-income countries. They find that anaesthesia contributes 2·8% of all maternal deaths in these settings. Although this G

• br Alegato y ret rica de

  2019-06-26

  

  Alegato y retórica de la violencia en la Brevíssima relación de la destruyción de las Indias En el año 1552 fray Bartolomé de las Casas, en Sevilla, se ocupa de dar Study Interventions la imprenta ocho de sus principales escritos, entre ellos la Brevíssima relación, compuesta diez años antes: “Y

• br Case A year old Caucasian male with

  2019-06-26

  

  Case 4 A 59 year old Caucasian male with a history of chronic renal insufficiency was transferred to our intensive care unit from an outside hospital, intubated secondary to respiratory failure and severe mucositis. He arrived on multiple broad spectrum enough for treatment of healthcare associa

• br Discussion Case reports of successful chemotherapy desens

  2019-06-26

  

  Discussion Case reports of successful chemotherapy desensitizations have been described for platinum agents, taxanes, anthracyclines, rituximab [8], and cytarabine [9], but not specifically clofarabine. For older patients with relapsed AML that are not candidates to receive anthracycline therapy,

• For many decades scientists have

  2019-06-26

  

  For many decades, scientists have warned that human activity is pushing life on our planet beyond the point of no return. In the Earth\'s history there have been five mass extinction events, most recently the Cretaceous–Tertiary mass extinction that occurred almost 65 million years ago and was thoug

• Previous studies have demonstrated localization of miR stain

  2019-06-26

  

  Previous studies have demonstrated localization of miR-21 staining in stromal CGS 21680 of OSCC associated with the tongue and mouth floor—this might be a useful prognostic predictor. We also observed miR-21 staining in the stromal cells of tumors. However, since multiple lines of evidence indicate

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