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In the present study we firstly confirmed the
2019-05-08
In the present study, we firstly confirmed the resistance of osteosarcoma U2OS LY2228820 to doxorubicin under hypoxia via inhibiting the drug-induced apoptosis. The hypoxia pre-treatment could significantly ameliorate the viability reduction in U2-os cells which were treated with doxorubicin with 5
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Jes s estigmatiz en su predicaci n la injusticia social
2019-05-07
“Jesús estigmatizó en su predicación la injusticia social de su tiempo” y lo hizo sin compasión, decía Cullmann. “Jesús anuncia que, a la luz del Reino que ha de venir, la diferencia entre ricos y pobres es contraria a la voluntad divina. Ese juicio sobre el orden social presente es, de suyo, revolu
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The diagnosis of PTC based on the Modified Dandy Criteria
2019-05-07
The diagnosis of PTC, based on the Modified Dandy Criteria, is made when a patient exhibits an elevated LP opening pressure above 25cm H20 with normal CSF composition and radiologic findings, and no other explanation for the rise in intracranial pressure [6]. The most common presenting symptom occur
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Cholangiopathies are a group of rare diseases whose
2019-05-07
Cholangiopathies are a group of rare diseases whose primary or secondary target is the cholangiocyte. The onset and subsequent development processes of cholangiopathies are extremely diverse, with causes that are genetic, neoplastic, immune-mediated, idiopathic, infectious, and toxin- or drug-induce
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These studies demonstrated that the levels of essential
2019-05-07
These studies demonstrated that the levels of essential ptc124 in healthy pregnant women were significantly different from those of the general population. There is a need to evaluate more pregnant women, especially from different races, for the purpose of establishing specific normative levels of
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To raise awareness of the importance
2019-05-07
To raise awareness of the importance of birth registration and to discuss strategies to promote it, UNICEF is launching two related publications on the anniversary of the organisation\'s founding is a statistical analysis spanning 161 countries and presenting the latest available country data and es
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Seg n Patricia Fagen en su estudio cl
2019-05-07
Según Patricia Fagen, en su estudio clásico sobre el exilio español, “un numero sorprendente de jóvenes participaron en el Movimiento 1959 y muchos más hubieran participado si hubiesen creído que había algo significativo con lo que hubieran podido contribuir”. El espíritu de ruptura con las disputas
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Azacitidine was administered at a dose
2019-05-07
Azacitidine was administered at a dose of 75mg/m2/daily subcutaneously for 7 consecutive days every 28days. Transient neutropenia was observed until the seventh ochratoxin a of the azacitidine treatment was completed. A gradual increase in his blood cell count was noted and the patient eventually be
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br For more than a
2019-05-07
For more than a decade, WHO has focused its efforts against infectious diseases in Africa on HIV, tuberculosis, and malaria. HIV benefited from unprecedented efforts to enable diagnosis and prevention of transmission and to provide therapy at low cost. National networks of health clinics, transpor
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lysophosphatidic acid br Interaction between MSCs and immune
2019-05-07
Interaction between MSCs and immune cells MSCs have also been shown to possess broad immunoregulatory capabilities and are capable of influencing both adaptive and innate immune responses. MSCs inhibit immune lysophosphatidic acid proliferation and maturation and suppress immune reactions both i
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hepititis b Based on our subgrouping according to ECG patter
2019-05-07
Based on our subgrouping according to ECG patterns, men were predominant in the Br, ER, or Br–ER group compared with the true IVF group (Table 1). This sex difference was also noted in previous reports [15–17] and may be partially due to different levels of Ito channel expression between sexes [18].
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Recently denosumab demonstrated a significant
2019-05-07
Recently, denosumab demonstrated a significant delay in the onset of detectable bone lesions in men with castration resistant prostate cancer compared to placebo . This could indicate some kind of efficacy of the compound as anticancer agent and consequently an indirect confirmation of the role of R
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br To see how the quantity of
2019-05-07
To see how the quantity of osteosarcoma in vitro studies developed overtime, we set out to systematically identify all the drugs that have been tested on osteosarcoma ion channels in vitro in the past two decades. A PubMed search strategy was compiled which can be found in Supplementary data 1. T
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Introduction Multiple myeloma MM is the most frequent cancer
2019-05-06
Introduction Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with 80–90% of patients developing bone lesions during their disease course [1]. Myeloma bone lesions are purely osteolytic and are associated with severe and debilitating bone pain, pathologic fractures, hyperca
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Importa recordar que el intelectual
2019-05-06
Importa recordar que el intelectual académico siempre se ha sentido incómodo en su propia piel. Leer y escribir rigurosamente pueden ser actos radicales en sí, pero la relación del intelectual y la academia suele exigir sospecha, mucho más que la del artista y el mercado, o la del político y el part
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