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Finally we have a means of monitoring
2019-06-15
Finally, we have a means of monitoring pace–sense conductor failure in an ICD lead. LIA™ (Lead Integrity Alert, Medtronic, Minneapolis, MN, USA) is a detection system for ICD pace–sense conductor failure [16]. Remote monitoring is also effective using this method of lead failure detection [17]. Howe
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Any abnormality causing a loss of function in
2019-06-15
Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -
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br Discovery of S PR as a CBA sensor in
2019-06-15
Discovery of S1PR2 as a CBA sensor in the liver Early studies reported that activation of the ERK1/2 and AKT signaling pathways by CBAs was PTX-sensitive, suggesting a role for a Gαi-linked GPCR. To identify which GPCR activates the ERK1/2 and AKT signaling pathways, the cDNAs encoding more than
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Por supuesto para que el
2019-06-15
Por supuesto, para que el reconocimiento de los campesinos se constituya como nacional es necesaria una relación de poder bastante poco estudiada, en la que sectores oligárquicos podrían representar a los campesinos. Esta articulación sería desestabilizada de vez en cuando, como por ejemplo cuando S
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Funding None Declaration of interests br
2019-06-14
Funding None. Declaration of interests Abstract Background Millennium Development Goal (MDG) 6 focused on halting the spread of HIV/AIDS. Since this goal was established, more development assistance for health has been devoted to combat HIV/AIDS in low-income and middle-income countries than an
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br In December consecutive waves of major
2019-06-14
In December, 2016, consecutive waves of major smog shrouded China, particularly the North China Plain and Sichuan Basin, resulting in suspended schools, halted industrial production, and heavy traffic. Atmospheric levels of fine particulate synthesi (PM) spiked to more than 500 μg/m in Henan and
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Stimulated IUI is much more effective than
2019-06-14
Stimulated IUI is much more effective than natural HG-9-91-01 manufacturer or controlled ovarian hyperstimulation treatment. In four randomized trials of patients with unexplained subfertility, pregnancy rates were higher when IUI was performed in stimulated cycles than in natural cycles [odds ratio
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Introduction Tumor metastases of the skeleton occur
2019-06-14
Introduction Tumor metastases of the skeleton occur in up to 80% of patients in progressed stages of cancer, most commonly in cases of breast, lung, prostate, kydney and thyroid tumors [1,2]. Bone metastases are often associated with pathologic fractures, hypercalcemia and spinal cord compression,
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br ECM cancer and metastasis For
2019-06-14
ECM, cancer and metastasis For melatonin receptor agonists to become cancerous they must acquire the ability to survive, grow and invade leading to malignant transformation, tumour formation and ultimately overt secondary metastasis. Abnormal ECM can promote these abilities and is a well-document
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br Results There were cases where cryotherapy was
2019-06-14
Results There were 232 cases where cryotherapy was used in 214 patients between 1994 and 2015. There were 96 male and 118 female. The age of patients ranged from 4 to 95. All patients had undergone imaging studies for evaluation. A majority of cases consisted of active or aggressive benign tumors
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br Conclusion Accumulating clinical data suggest the presenc
2019-06-14
Conclusion Accumulating clinical data suggest the presence of a genetic component in the pathogenesis of AF. In addition to the gene mutations identified in familial AF, the candidate gene approach and GWAS identified genetic risks in the non-familial form of AF. In multiple Western populations,
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br Introduction Patients with advanced breast
2019-06-14
Introduction Patients with advanced breast, prostate, lung and colo-rectal cancer frequently develop bone metastases (BMs). These lesions may be asymptomatic or may cause pain, pathologic fractures, malignant hypercalcemia, epidural spinal cord compression and/or shorten survival [1]. The underly
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br Discussion There were recurrences out of patients of whic
2019-06-14
Discussion There were 2 recurrences (8.3%¸ 2 out of 24 patients), 1 of which occurred immediately following the procedure. In this patient, SVT was not induced with programmed atrial or ventricular stimulations after the ablation of accessory pathway. Ventriculoatrial conduction was through the A
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gli1 Emergency care inherently addresses the wide array of i
2019-06-14
Emergency care inherently addresses the wide array of illness and injury, including traumatic injuries, surgical disease, acute complications of chronic illness (eg, strokes, myocardial infarction, diabetic ketoacidosis, complications of HIV, tuberculosis, hepatitis C, and other chronic infections),
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La Brev ssima relaci n de la destruyci n
2019-06-14
La Brevíssima relación de la destruyción de las Indias de fray Bartolomé de las Casas, fechada el 8 de diciembre de 1542, se publica en el año 1552 (“… fue rogado e importunado que destas postreras pusiesse algunas por brevedad por escrito”). Finalmente es condenada en 1660 por el Tribunal de la Inq
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