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br Materials and methods br Results br
2019-05-31

Materials and methods Results Discussion In recent years, it has been revealed that miRNAs are critical members of complex regulatory systems. SNPs or mutations occurring in the miRNA gene region may disturb the properties of miRNAs and result in defect in protein translation of target mRNA
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br Quantitative analysis The quantitative analysis is based
2019-05-31

Quantitative analysis The quantitative analysis is based on modeling the concentration change of the contrast agent using pharmacokinetic modeling techniques. An initial conversion of SI to concentration values is needed. Concentration vs time curves are then fitted using a bi-compartmental PK mo
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In an effort to determine whether the primary tumour might
2019-05-31

In an effort to determine whether the primary tumour might be responsible for “fertilising” the bone “soil” ready for the cancer “seed”, we recently found that a hypoxic gene signature, and more specifically the secreted enzyme lysyl oxidase (LOX) was closely associated with bone metastasis, specifi
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br Ethics br Funding br Conflicts of interest br Acknowledgm
2019-05-31

Ethics Funding Conflicts of interest Acknowledgments Case A 68-year-old man with palpitations was referred to our center for catheter ablation because of drug-refractory atrial fibrillation (AF). The preoperative multidetector computed tomography showed a congenital vascular anomaly:
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En textos m s recientes Aboy
2019-05-31

En textos más recientes, Aboy Carlés profundiza esta distinción y reconoce que no toda identidad tiene una pretensión hegemónica y propone distinguir entre identidades totales, identidades parciales e identidades con pretensión hegemónica de acuerdo con el modo de procesar la relación entre la parte
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In acute ventricular perforations the
2019-05-31

In acute ventricular perforations, the lead can be repositioned and followed with serial echocardiograms to monitor resolution of perforation and to detect deterioration that would require immediate intervention. In the subacute and delayed perforations, if there is no bleeding in the mediastinum, t
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br Material and methods br Results
2019-05-31

Material and methods Results Discussion Conclusions Conflict of interest Introduction Scoliosis forms a complex curve in all three planes, not only in the coronal plane, leading to deformities caused by the self-rotating movement of the spine [1]. Spinal anomalies may impair cardio
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According to the labeling of dabigatran in Japan patients
2019-05-31

According to the labeling of dabigatran in Japan, patients to be considered for the prescription of the lower dose of 220mg/day are as follows: (1) aged ≥70 years, (2) with moderate renal impairment (ClCr 30–50mL/min), (3) concomitant use of a p-glycoprotein inhibitor, and (4) history of hemorrhage
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Es as como se establece la relaci n entre los
2019-05-30

Es así como se establece la relación entre los dos relatos: la novela histórica es parte de la novela policíaca y ambas tienden al mismo fin trágico, la muerte de su respectivo héroe. Al respecto, conviene hacer ciertas acotaciones sobre el término de “héroe”. Si bien en este último pasaje citado de
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En este mismo orden de ideas
2019-05-30

En este mismo orden de ideas, Brian McHale comenta que: Pons señala: Con esto, Pons reconoce que las novelas históricas contemporáneas de la región “no sólo plantean el problema de incluir en la reescritura de la historia lo excluido, lo silenciado, olvidado y reprimido por y en la historia, sino
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domoic acid br A modo de conclusi n La re visi
2019-05-30

A modo de conclusión La re/visión que se ha propuesto en el presente escrito recoge el sentido que le da Adrienne Rich al término: revisar es volver a mirar desde un posicionamiento crítico en un presente, desde el que se tiene una perspectiva (temporal) de cómo ha sido la suerte del fenómeno que
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HCV does not kill the
2019-05-30

HCV does not kill the tyrosol it infects, but triggers an immune-mediated inflammatory response (hepatitis) that either rapidly clears the infection or slowly destroys the liver, causing the development of HCC and cirrhosis. The outcome is largely determined by the efficiency of the antiviral immun
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Introduction Focused ultrasound FUS sonication in the presen
2019-05-30

Introduction Focused ultrasound (FUS) sonication in the presence of microbubbles (MB) can disrupt the BBB, increasing its permeability. This type of disruption is transient and reversible, and does not damage neural cells. The oscillation and destruction of microbubbles as well as microstreaming an
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We conducted a retrospective analysis to compare a
2019-05-30

We conducted a retrospective analysis to compare a BMD-alone strategy, versus BMD+FRAX® and BMD+FRAX®+TBS screening strategies. To our knowledge, this constitutes the first study to assess the relative contributions of FRAX® and TBS. In our cohort, FRAX®+BMD identified 9 (9%) additional patients at
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Any abnormality causing a loss of function
2019-05-30

Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -
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