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Scutellaria moniliorrhiza Komarov Labiatae is a
2023-11-27

Scutellaria moniliorrhiza Komarov (Labiatae) is a perennial herb and mainly distributed in Jilin province, China. In traditional Chinese medicine, the whole plants have been used to clear away heat-evil, expel superficial evils, eliminate stasis and reduce edema (He et al., 2012). In previous phytoc
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In this study we obtained the absorbance and photoluminescen
2023-11-27

In this study, we obtained the absorbance and photoluminescence (PL) of Cy5 hydrazide (non-sulfonated) receptor polymerized with various types of actin-binding proteins in order to probe the actin structures in situ without labeling. Both optical measurements have been useful in examining biomateria
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The rapidity of this specific immunosuppressive therapy sugg
2023-11-27

The rapidity of this specific immunosuppressive therapy suggests that it inhibits or apoptoses plasma cells. Most serum autoantibodies to AChR are produced by long-lived plasma cells residing in spleen and bone marrow. These terminally differentiated cells are resistant to most non-specific immunosu
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A large number of studies have
2023-11-24

A large number of studies have shown that oxidative stress is involved in the pathophysiological process of ventricular remodeling and is associated with left ventricular dysfunction (Hori and Nishida, 2009, Lord et al., 2010). The generation of reactive oxygen species (ROS) that exceeds anti-oxidat
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Because R gene is positively regulated by T and
2023-11-24

Because 5α-R2 gene is positively regulated by T and in the prostate gland (Torres et al., 2003), and our BPA-treated rats showed decreased circulating T and probably intraprostatic androgen levels, it might be responsible for the decrease of 5α-R2 expression. However, in a previous work using castra
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br Materials and methods br Results br Discussion I
2023-11-24

Materials and methods Results Discussion I/R injury is characterized by myocardial damage triggered by the ischemic insult followed by reperfusion injury. While the primary insult depends mainly on the severity and duration of blood flow restriction and the breakdown of ATP-dependent 76 7
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In addition understanding the relationship between human met
2023-11-24

In addition, understanding the relationship between human metabolic processes and dietary antioxidant intake would provide opportunities for altering the diet to improve health (Prior, 2015). Prior et al. (2007) emphasized that excess reactive oxygen species, which occurred during the metabolism of
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BQ-123 br Emerging Vascular Mechanisms of AA
2023-11-24

Emerging Vascular Mechanisms of AA Therapy Resistance Experimental and clinical evidence indicates that physiological angiogenesis generates blood vessels capable of restoring perfusion [1], whereas tumoral angiogenesis gives rise to vessels that are structurally and functionally abnormal, therei
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Glycerol dehydratase GDHt EC is a key enzyme for
2023-11-24

Glycerol dehydratase (GDHt, EC 4.2.1.30) is a key enzyme for the bioconversion of glycerol into the value-added chemicals and thereby has recently attracted a great deal of attention as an essential component for metabolic engineering . GDHt carries out a radical-mediated turnover of glycerol into 3
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Activation of AhR is also known to upregulate the expression
2023-11-24

Activation of AhR is also known to upregulate the expression of AhRR (AhR repressor), an inhibitor protein of AhR [29]. However, the exact mechanism by which AhRR represses AhR signaling is not well understood. The initial study by Mimura and colleagues suggested that AhRR is capable of directly com
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Our findings establish a critical link
2023-11-24

Our findings establish a critical link between HemAC-Lm dimeric structure and cAMP synthesis that helps in explaining how globin-A domain influences AC domain. The following possible homodimeric structure of wild type full length HemAC-Lm has been proposed to explain the role of this globin-A domain
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br Materials and methods br Results br Discussion In the
2023-11-24

Materials and methods Results Discussion In the present study, we aimed to elucidate the contribution of adenosine receptors to vascular tone in mice with T1D. We showed that diabetes resulted in decreased A1 adenosine receptor-mediated contraction in the aorta, which was accompanied by inc
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We have previously reported alterations of the
2023-11-24

We have previously reported alterations of the thymus in AChR-MG patients, especially in their germinal center CP-809101 hydrochloride synthesis (defined as CD19+CD38+ cells by flow cytometric analysis). First, we found that, in MG thymi, this subset failed to show the normal down-regulation of Bcl
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br Conclusion br Conflicts of
2023-11-24

Conclusion Conflicts of interest Introduction RNA interference is a specific post-transcriptional gene silencing mechanism within a cell via the transfection of microRNAs (miRNA), exogenous small interfering RNAs (siRNA) or small hairpin RNAs (shRNA) [1–3]. Transfection of shRNA can be done
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Despite functional studies demonstrating the role of HT in
2023-11-23

Despite functional studies demonstrating the role of 5-HT in ureteral contractility, the source of endogenous 5-HT in the ureter is unclear. Since 5-HT-containing enterochromaffin cells, which are present in the gastrointestinal tract, could not be found in the ureter (Nocito et al., 2007, Ripoche,
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