• In order to get a better understanding of this

  2023-08-28

  

  In order to get a better understanding of this synergy, we tested the effect of preliminary incubation of find protocol with non-stimulating concentrations of gonadotropins or FSK before subsequent stimulation by FSK or gonadotropins alone, also at sub-stimulating concentrations. We observed that h

• br Acknowledgments We thank the anonymous reviewers for

  2023-08-28

  

  Acknowledgments We thank the anonymous reviewers for their constructive comments on the manuscript, and also thank Dr. Hans-U. Dahms for his comments on the manuscript. This work was supported by a grant from the National Research Foundation (2009-0071218) funded to Young-Mi Lee. This work was al

• It has recently been reported that plasma

  2023-08-28

  

  It has recently been reported that plasma and synovial fluid levels of autotaxin correlate with severity of knee OA. Synovial fibroblasts isolated from OA patients express significant amounts of autotaxin mRNA, and this increase in autotaxin NS-398 receptor could lead to increased production of LPA

• Production of reactive oxygen species ROS during RSV infecti

  2023-08-28

  

  Production of reactive oxygen species (ROS) during RSV infection is one the important ways that neutrophils can injure the lungs [2], [24], [25]. Lipoxygenases are considered as an important source of producing ROS inside the MK 886 mg [26]. Several studies have indicated that the 12/15-LOX is a pr

• ARG I is one of the most important mammalian enzymes

  2023-08-28

  

  ARG I is one of the most important mammalian enzymes responsible for nitrogen metabolism since it comprises the main route for the elimination of excess nitrogen resulting from amino purinergic receptors and nucleotide metabolism [18]. ARG I deficiency leads to hyperargininemia, characterized by pr

• br Materials and Methods br Results br Discussion XHP

  2023-08-28

  

  Materials and Methods Results Discussion XHP is a traditional Chinese anti-cancer medicine that is widely used for the treatment and adjuvant treatment of breast cancer. XHP has been shown to induce apoptosis in various breast cancer Epirubicin HCl in vitro, including Hs578T, MCF-7, and MD

• Expression of Twist and the AR are increased

  2023-08-28

  

  Expression of Twist1 and the AR are increased by oxidative stress, but the change in the receptor (mRNA/protein) is lost after treatment with siRNAs that target Twist 1 (Shiota et al., 2010). Twist 1 was found to bind to E-boxes, 5′-CANNTG-3′, in the proximal promoter (−442 to +51 bp) and upstream r

• Consistent with the in vitro results memantine ameliorated A

  2023-08-28

  

  Consistent with the in vitro results, memantine ameliorated Aβ-induced cytotoxicity in rat primary cortical cultures. Studies reported that memantine protected neurons against the damage caused by aggregated Aβ40 or Aβ42 oligomers in vivo[26], [27]. These results suggest that, in addition to its neu

• HsALDH enzyme has been purified for the first time in

  2023-08-28

  

  HsALDH enzyme has been purified for the first time in our laboratory from human saliva and has been kinetically characterized using different aromatic substrates [35]. Also, the effect of some common substances frequently encountered by the enzyme in the oral cavity (such as ethanol, hydrogen peroxi

• Interestingly hypoxia and an enhanced Warburg effect ultimat

  2023-08-28

  

  Interestingly, hypoxia and an enhanced Warburg effect ultimately lead to increased lactate production. The accumulation of lactate results in an acidic tumor microenvironment, which induces local inflammation. Lactate also promotes the polarization of macrophages that express immunosuppressive argin

• br Experimental procedure br Introduction Migraine is

  2023-08-28

  

  Experimental procedure Introduction Migraine is a debilitating neurovascular disorder characterized by recurring unilateral pulsating headaches of moderate to severe intensity, associated with nausea, photophobia and/or phonophobia, lasting from 4 to 72 h (Headache Classification Committee of

• br Results br Discussion Members of the PfkB family

  2023-08-26

  

  Results Discussion Members of the PfkB family of proteins, which exhibit AK activity, have only been found in the eukaryotic organisms in the past. Hence, the report of a PfkB family protein in MTub that exhibited AK activity was of much interest, and it necessitated closer examination of its

• Diabetes or inflammation is associated with up

  2023-08-26

  

  Diabetes or inflammation is associated with up-regulation of A2AAR (Pang et al., 2010). High levels of A2AARs are found in macrophages and microglial cells that are poised, on activation, to abrogate the immune response (Trincavelli et al., 2008). In addition, hyperglycemia is associated with increa

• Multiple ASD susceptibility genes converge

  2023-08-26

  

  Multiple ASD susceptibility genes converge on cellular pathways that intersect at the postsynaptic site of glutamatergic synapses (Bourgeron, 2015; Peca & Feng, 2012), the development and maturation of synaptic contacts (Gilman et al., 2011) or synaptic transmission (Li et al., 2014). The majority o

• Plant material and growth conditions Arabidopsis

  2023-08-26

  

  Plant material and growth conditions. Arabidopsis thaliana ecotype Columbia was grown on a mixture of soil, vermiculite, and perlite (4:2:1) with a 16h light/8h dark WEHI-539 in a temperature-controlled growth room (22°C), unless indicated otherwise. Molecular cloning and plant transformation. The

15904 records 275/1061 page Previous Next First page 上5页 271272273274275 下5页 Last page